Pulsatile stretch as a novel modulator of amyloid precursor protein processing and associated inflammatory markers in human cerebral endothelial cells

Amyloid β (Aβ) deposition is a hallmark of Alzheimer’s disease (AD). Vascular modifications, including altered brain endothelial cell function and structural viability of the blood-brain barrier due to vascular pulsatility, are implicated in AD pathology. Pulsatility of phenomena in the cerebral vas...

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Detalles Bibliográficos
Autores principales: Gangoda, Sumudu V. S., Avadhanam, Bhargava, Jufri, Nurul F., Sohn, Eun Hwa, Butlin, Mark, Gupta, Vivek, Chung, Roger, Avolio, Alberto P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786097/
https://www.ncbi.nlm.nih.gov/pubmed/29374229
http://dx.doi.org/10.1038/s41598-018-20117-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786097/
https://www.ncbi.nlm.nih.gov/pubmed/29374229
http://dx.doi.org/10.1038/s41598-018-20117-6

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