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Elevated Proportions of Deleterious Genetic Variation in Domestic Animals and Plants

A fraction of genetic variants segregating in any population are deleterious, which negatively impacts individual fitness. The domestication of animals and plants is associated with population bottlenecks and artificial selection, which are predicted to increase the proportion of deleterious variant...

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Detalles Bibliográficos
Autores principales: Makino, Takashi, Rubin, Carl-Johan, Carneiro, Miguel, Axelsson, Erik, Andersson, Leif, Webster, Matthew T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786255/
https://www.ncbi.nlm.nih.gov/pubmed/29325102
http://dx.doi.org/10.1093/gbe/evy004