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Oxygen-Sensitive Remodeling of Central Carbon Metabolism by Archaic eIF5B

The eukaryotic translation initiation factor 5B (eIF5B) is a homolog of IF2, an ancient translation factor that enables initiator methionine-tRNAi(Met) (met-tRNAi(Met)) loading on prokaryotic ribosomes. While it can be traced back to the last universal common ancestor, eIF5B is curiously dispensable...

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Detalles Bibliográficos
Autores principales: Ho, J.J. David, Balukoff, Nathan C., Cervantes, Grissel, Malcolm, Petrice D., Krieger, Jonathan R., Lee, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786279/
https://www.ncbi.nlm.nih.gov/pubmed/29298419
http://dx.doi.org/10.1016/j.celrep.2017.12.031