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Interactions between species introduce spurious associations in microbiome studies

Microbiota contribute to many dimensions of host phenotype, including disease. To link specific microbes to specific phenotypes, microbiome-wide association studies compare microbial abundances between two groups of samples. Abundance differences, however, reflect not only direct associations with t...

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Detalles Bibliográficos
Autores principales: Menon, Rajita, Ramanan, Vivek, Korolev, Kirill S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786326/
https://www.ncbi.nlm.nih.gov/pubmed/29338008
http://dx.doi.org/10.1371/journal.pcbi.1005939