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Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans
The pathogenic fungus Candida albicans can undergo phenotypic switching between two heritable states: white and opaque. This phenotypic plasticity facilitates its colonization in distinct host niches. The master regulator WOR1 is exclusively expressed in opaque phase cells. Positive feedback regulat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786334/ https://www.ncbi.nlm.nih.gov/pubmed/29337983 http://dx.doi.org/10.1371/journal.pgen.1007176 |