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The impact of ribosomal interference, codon usage, and exit tunnel interactions on translation elongation rate variation
Previous studies have shown that translation elongation is regulated by multiple factors, but the observed heterogeneity remains only partially explained. To dissect quantitatively the different determinants of elongation speed, we use probabilistic modeling to estimate initiation and local elongati...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786338/ https://www.ncbi.nlm.nih.gov/pubmed/29337993 http://dx.doi.org/10.1371/journal.pgen.1007166 |