Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe

Telomere maintenance critically depends on the distinct activities of telomerase, which adds telomeric repeats to solve the end replication problem, and RTEL1, which dismantles DNA secondary structures at telomeres to facilitate replisome progression. Here, we establish that reversed replication for...

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Detalles Bibliográficos
Autores principales: Margalef, Pol, Kotsantis, Panagiotis, Borel, Valerie, Bellelli, Roberto, Panier, Stephanie, Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786504/
https://www.ncbi.nlm.nih.gov/pubmed/29290468
http://dx.doi.org/10.1016/j.cell.2017.11.047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786504/
https://www.ncbi.nlm.nih.gov/pubmed/29290468
http://dx.doi.org/10.1016/j.cell.2017.11.047

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