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Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe
Telomere maintenance critically depends on the distinct activities of telomerase, which adds telomeric repeats to solve the end replication problem, and RTEL1, which dismantles DNA secondary structures at telomeres to facilitate replisome progression. Here, we establish that reversed replication for...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786504/ https://www.ncbi.nlm.nih.gov/pubmed/29290468 http://dx.doi.org/10.1016/j.cell.2017.11.047 |