A Spontaneous Mutation in Taar1 Impacts Methamphetamine-Related Traits Exclusively in DBA/2 Mice from a Single Vendor

Major gene effects on traits associated with substance use disorders are rare. Previous findings in methamphetamine drinking (MADR) lines of mice, bred for high or low voluntary MA intake, and in null mutants demonstrate a major impact of the trace amine-associated receptor 1 (Taar1) gene on a triad...

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Detalles Bibliográficos
Autores principales: Reed, Cheryl, Baba, Harue, Zhu, Zhen, Erk, Jason, Mootz, John R., Varra, Nicholas M., Williams, Robert W., Phillips, Tamara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786530/
https://www.ncbi.nlm.nih.gov/pubmed/29403379
http://dx.doi.org/10.3389/fphar.2017.00993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786530/
https://www.ncbi.nlm.nih.gov/pubmed/29403379
http://dx.doi.org/10.3389/fphar.2017.00993

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