Pin1 Promotes Regulated Necrosis Induced by Glutamate in Rat Retinal Neurons via CAST/Calpain2 Pathway

The purpose of the current study was to investigate whether peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (Pin1) can interact with calpastatin (CAST) and regulate CAST/calpain2, under excessive glutamate conditions, and subsequently regulate necrosis in rat retinal neurons. Glutamate trigge...

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Detalles Bibliográficos
Autores principales: Wang, Shuchao, Liao, Lvshuang, Wang, Mi, Zhou, Hongkang, Huang, Yanxia, Wang, Zhen, Chen, Dan, Ji, Dan, Xia, Xiaobo, Wang, Yong, Liu, Fengxia, Huang, Jufang, Xiong, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786546/
https://www.ncbi.nlm.nih.gov/pubmed/29403356
http://dx.doi.org/10.3389/fncel.2017.00425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786546/
https://www.ncbi.nlm.nih.gov/pubmed/29403356
http://dx.doi.org/10.3389/fncel.2017.00425

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