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Corticosterone Preexposure Increases NF-κB Translocation and Sensitizes IL-1β Responses in BV2 Microglia-Like Cells

Corticosterone (CORT), a critical mediator of the hypothalamus pituitary adrenal axis in rodents, is a stress hormone that is classically viewed as possessing immune-suppressive properties. CORT is now appreciated to also mediate the neuroimmune-priming effect of stress to innate-immune stimulation,...

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Detalles Bibliográficos
Autores principales: Liu, JiaJun, Mustafa, Sanam, Barratt, Daniel Thomas, Hutchinson, Mark Rowland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786551/
https://www.ncbi.nlm.nih.gov/pubmed/29403490
http://dx.doi.org/10.3389/fimmu.2018.00003