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Cathepsin K Localizes to Equine Bone In Vivo and Inhibits Bone Marrow Stem and Progenitor Cells Differentiation In Vitro

Selective inhibition of Cathepsin K (CatK) has a promising therapeutic potential for diseases associated with bone loss and osseous inflammation, such as osteoarthritis, periodontitis, and osteoporosis. In horses, stress-related bone injuries are common and accompanied by bone pain and inflammation...

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Detalles Bibliográficos
Autores principales: Hussein, Hayam, Boyaka, Prosper, Dulin, Jennifer, Russell, Duncan, Smanik, Lauren, Azab, Mohamed, Bertone, Alicia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Stem Cells and Regenerative Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786646/
https://www.ncbi.nlm.nih.gov/pubmed/29391749