What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis

Rapid and accurate drug susceptibility testing (DST) is essential for the treatment of multi- and extensively drug-resistant tuberculosis (M/XDR-TB). We compared the utility of genotypic DST assays with phenotypic DST (pDST) using Bactec 960 MGIT or Löwenstein-Jensen to construct M/XDR-TB treatment...

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Detalles Bibliográficos
Autores principales: Heyckendorf, Jan, Andres, Sönke, Köser, Claudio U., Olaru, Ioana D., Schön, Thomas, Sturegård, Erik, Beckert, Patrick, Schleusener, Viola, Kohl, Thomas A., Hillemann, Doris, Moradigaravand, Danesh, Parkhill, Julian, Peacock, Sharon J., Niemann, Stefan, Lange, Christoph, Merker, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786814/
https://www.ncbi.nlm.nih.gov/pubmed/29133554
http://dx.doi.org/10.1128/AAC.01550-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786814/
https://www.ncbi.nlm.nih.gov/pubmed/29133554
http://dx.doi.org/10.1128/AAC.01550-17

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