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What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis
Rapid and accurate drug susceptibility testing (DST) is essential for the treatment of multi- and extensively drug-resistant tuberculosis (M/XDR-TB). We compared the utility of genotypic DST assays with phenotypic DST (pDST) using Bactec 960 MGIT or Löwenstein-Jensen to construct M/XDR-TB treatment...
Autores principales: | Heyckendorf, Jan, Andres, Sönke, Köser, Claudio U., Olaru, Ioana D., Schön, Thomas, Sturegård, Erik, Beckert, Patrick, Schleusener, Viola, Kohl, Thomas A., Hillemann, Doris, Moradigaravand, Danesh, Parkhill, Julian, Peacock, Sharon J., Niemann, Stefan, Lange, Christoph, Merker, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786814/ https://www.ncbi.nlm.nih.gov/pubmed/29133554 http://dx.doi.org/10.1128/AAC.01550-17 |
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