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Associations between type I interferon and antiphospholipid antibody status differ between ancestral backgrounds

OBJECTIVE: The type I interferon pathway is activated in many patients with systemic lupus erythematosus (SLE), and anti-double-stranded DNA (dsDNA) and anti-RNA binding protein autoantibodies are correlated with high interferon-α (IFNα) activity. We studied whether antiphospholipid (APL) antibodies...

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Detalles Bibliográficos
Autores principales: Iwamoto, Taro, Dorschner, Jessica, Jolly, Meenakshi, Huang, Xiangyang, Niewold, Timothy B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786906/
https://www.ncbi.nlm.nih.gov/pubmed/29387437
http://dx.doi.org/10.1136/lupus-2017-000246