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Mouse models of lupus: what they tell us and what they don’t

Lupus is a complex heterogeneous disease characterised by autoantibody production and immune complex deposition followed by damage to target tissues. Animal models of human diseases are an invaluable tool for defining pathogenic mechanisms and testing of novel therapeutic agents. There are perhaps m...

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Detalles Bibliográficos
Autores principales: Richard, Mara Lennard, Gilkeson, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786947/
https://www.ncbi.nlm.nih.gov/pubmed/29387435
http://dx.doi.org/10.1136/lupus-2016-000199