MicroRNA-146a Overexpression Impairs the Positive Selection during T Cell Development

MicroRNAs play crucial roles in modulating immune system. miR-146a, a potent feedback suppressor of NF-κB signaling, was shown to limit the innate immune response and myelopoiesis in a knockout mouse model. Here, we observed high lymphopoiesis demonstrated as mild splenomegaly and severe lymphadenop...

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Detalles Bibliográficos
Autores principales: Li, Zinan, Zhang, Siya, Wan, Ying, Cai, Menghua, Wang, Weiqing, Zhu, Yuli, Li, Zhen, Hu, Yu, Wang, Huaishan, Chen, Hui, Cui, Lianxian, Zhang, Xuan, Zhang, Jianmin, He, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787067/
https://www.ncbi.nlm.nih.gov/pubmed/29410664
http://dx.doi.org/10.3389/fimmu.2017.02006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787067/
https://www.ncbi.nlm.nih.gov/pubmed/29410664
http://dx.doi.org/10.3389/fimmu.2017.02006

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