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Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors

Primary cilia are microtubule-based organelles, which protrude from the plasma membrane and receive a wide range of extracellular signals. Various cilia use G protein-coupled receptors (GPCRs) for the detection of these signals. For instance, vertebrate rod photoreceptors use their cilia (also calle...

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Detalles Bibliográficos
Autores principales: Brooks, Celine, Murphy, Joseph, Belcastro, Marycharmain, Heller, Daniel, Kolandaivelu, Saravanan, Kisselev, Oleg, Sokolov, Maxim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787109/
https://www.ncbi.nlm.nih.gov/pubmed/29410614
http://dx.doi.org/10.3389/fnmol.2018.00016