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Patterns of variation in cis-regulatory regions: examining evidence of purifying selection

BACKGROUND: With only 2 % of the human genome consisting of protein coding genes, functionality across the rest of the genome has been the subject of much debate. This has gained further impetus in recent years due to a rapidly growing catalogue of genomic elements, based primarily on biochemical si...

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Detalles Bibliográficos
Autores principales: Naidoo, Thijessen, Sjödin, Per, Schlebusch, Carina, Jakobsson, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787233/
https://www.ncbi.nlm.nih.gov/pubmed/29373957
http://dx.doi.org/10.1186/s12864-017-4422-y