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Unique depot formed by an oil based vaccine facilitates active antigen uptake and provides effective tumour control

BACKGROUND: Oil emulsions are commonly used as vaccine delivery platforms to facilitate slow release of antigen by forming a depot at the injection site. Antigen is trapped in the aqueous phase and as the emulsion degrades in vivo the antigen is passively released. DepoVax™ is a unique oil based del...

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Detalles Bibliográficos
Autores principales: Brewer, Kimberly D., Weir, Genevieve M., Dude, Iulia, Davis, Christa, Parsons, Cathryn, Penwell, Andrea, Rajagopalan, Rajkannan, Sammatur, Leeladhar, Bowen, Chris V., Stanford, Marianne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787234/
https://www.ncbi.nlm.nih.gov/pubmed/29374458
http://dx.doi.org/10.1186/s12929-018-0413-9