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Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism

BACKGROUND: Our aim was to evaluate lipid trafficking and inflammatory response of macrophages exposed to lipoproteins from subjects with moderate to severe chronic kidney disease (CKD), and to investigate the potential benefits of activating cellular cholesterol transporters via liver X receptor (L...

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Detalles Bibliográficos
Autores principales: Kaseda, Ryohei, Tsuchida, Yohei, Yang, Hai-Chun, Yancey, Patricia G., Zhong, Jianyong, Tao, Huan, Bian, Aihua, Fogo, Agnes B., Linton, Mac Rae F., Fazio, Sergio, Ikizler, Talat Alp, Kon, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787279/
https://www.ncbi.nlm.nih.gov/pubmed/29374468
http://dx.doi.org/10.1186/s12882-018-0814-8