MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria

MacroD1 is a macrodomain containing protein that has mono-ADP-ribose hydrolase enzymatic activity toward several ADP-ribose adducts. Dysregulation of MacroD1 expression has been shown to be associated with the pathogenesis of several forms of cancer. To date, the physiological functions and sub-cell...

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Detalles Bibliográficos
Autores principales: Agnew, Thomas, Munnur, Deeksha, Crawford, Kerryanne, Palazzo, Luca, Mikoč, Andreja, Ahel, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787345/
https://www.ncbi.nlm.nih.gov/pubmed/29410655
http://dx.doi.org/10.3389/fmicb.2018.00020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787345/
https://www.ncbi.nlm.nih.gov/pubmed/29410655
http://dx.doi.org/10.3389/fmicb.2018.00020

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