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MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria
MacroD1 is a macrodomain containing protein that has mono-ADP-ribose hydrolase enzymatic activity toward several ADP-ribose adducts. Dysregulation of MacroD1 expression has been shown to be associated with the pathogenesis of several forms of cancer. To date, the physiological functions and sub-cell...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787345/ https://www.ncbi.nlm.nih.gov/pubmed/29410655 http://dx.doi.org/10.3389/fmicb.2018.00020 |