Cargando…

Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer

Although paclitaxel is routinely prescribed for the treatment of epithelial ovarian cancer (EOC), paclitaxel resistance is common in EOC and correlates with short survival of patients. A previous pharmacogenomic study revealed the importance of cyclin-dependent kinase 1 (CDK1) activity in a response...

Descripción completa

Detalles Bibliográficos
Autores principales: Byun, Mi Ran, Choi, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787417/
https://www.ncbi.nlm.nih.gov/pubmed/29416675
http://dx.doi.org/10.18632/oncotarget.23133