Mechanism of action and efficacy of LY2109761, a TGF-β receptor inhibitor, targeting tumor microenvironment in liver cancer after TACE

TACE (transcatheter arterial chemoembolization) has been recognized as an effective palliative treatment option for patients with HCC, however, the medium-long term efficacy of it remains modest. LY2109761, a TGF-β receptor inhibitor, was confirmed to reduce tumor cell growth, intravasation, and met...

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Detalles Bibliográficos
Autores principales: He, Xiaojun, Guo, Xiaopeng, Zhang, Hongsen, Kong, Xiangchuang, Yang, Fan, Zheng, Chuansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787425/
https://www.ncbi.nlm.nih.gov/pubmed/29416682
http://dx.doi.org/10.18632/oncotarget.23193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787425/
https://www.ncbi.nlm.nih.gov/pubmed/29416682
http://dx.doi.org/10.18632/oncotarget.23193

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