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Mechanism of action and efficacy of LY2109761, a TGF-β receptor inhibitor, targeting tumor microenvironment in liver cancer after TACE
TACE (transcatheter arterial chemoembolization) has been recognized as an effective palliative treatment option for patients with HCC, however, the medium-long term efficacy of it remains modest. LY2109761, a TGF-β receptor inhibitor, was confirmed to reduce tumor cell growth, intravasation, and met...
Autores principales: | He, Xiaojun, Guo, Xiaopeng, Zhang, Hongsen, Kong, Xiangchuang, Yang, Fan, Zheng, Chuansheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787425/ https://www.ncbi.nlm.nih.gov/pubmed/29416682 http://dx.doi.org/10.18632/oncotarget.23193 |
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