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LGR5 and LGR6 in stem cell biology and ovarian cancer

Wnt signaling plays a fundamental role in patterning of the embryo and maintenance of stem cells in numerous epithelia. Epithelial stem cells are closeted in niches created by surrounding differentiated cells that express secreted Wnt and R-spondin proteins that influence proliferation rate and fate...

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Detalles Bibliográficos
Autores principales: Schindler, Adam J., Watanabe, Arisa, Howell, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787443/
https://www.ncbi.nlm.nih.gov/pubmed/29416699
http://dx.doi.org/10.18632/oncotarget.20178