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Deguelin suppresses angiogenesis in human hepatocellular carcinoma by targeting HGF-c-Met pathway

Angiogenesis plays a crucial role in the development of human hepatocellular carcinoma (HCC). In the present study, we found a natural compound, deguelin, has a profound anti-angiogenesis effect on HCC. Deguelin suppressed vascular endothelial growth factor (VEGF)-induced human umbilical vascular en...

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Detalles Bibliográficos
Autores principales: Li, Ming, Yu, Xinfang, Li, Wei, Liu, Ting, Deng, Gang, Liu, Wenbin, Liu, Haidan, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787453/
https://www.ncbi.nlm.nih.gov/pubmed/29416603
http://dx.doi.org/10.18632/oncotarget.22077