Cargando…
SOX9-PDK1 axis is essential for glioma stem cell self-renewal and temozolomide resistance
Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor with limited therapeutic options. Glioma stem cell (GSC) is thought to be greatly responsible for glioma tumor progression and drug resistance. But the molecular mechanisms of GSC deriving recurrence and drug resistance are...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787456/ https://www.ncbi.nlm.nih.gov/pubmed/29416606 http://dx.doi.org/10.18632/oncotarget.22773 |