SOX9-PDK1 axis is essential for glioma stem cell self-renewal and temozolomide resistance

Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor with limited therapeutic options. Glioma stem cell (GSC) is thought to be greatly responsible for glioma tumor progression and drug resistance. But the molecular mechanisms of GSC deriving recurrence and drug resistance are...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Xu, Xiaoshan, Liu, Nan, Cheng, Yingduan, Jin, Weilin, Zhang, Pengxing, Wang, Xin, Yang, Hongwei, Liu, Hui, Tu, Yanyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787456/
https://www.ncbi.nlm.nih.gov/pubmed/29416606
http://dx.doi.org/10.18632/oncotarget.22773

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