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Three-dimensional tumor model mimics stromal – breast cancer cells signaling

Tumor stroma is a major contributor to the biological aggressiveness of cancer cells. Cancer cells induce activation of normal fibroblasts to carcinoma-associated fibroblasts (CAFs), which promote survival, proliferation, metastasis, and drug resistance of cancer cells. A better understanding of the...

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Detalles Bibliográficos
Autores principales: Ham, Stephanie Lemmo, Thakuri, Pradip Shahi, Plaster, Madison, Li, Jun, Luker, Kathryn E., Luker, Gary D., Tavana, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787462/
https://www.ncbi.nlm.nih.gov/pubmed/29416611
http://dx.doi.org/10.18632/oncotarget.22922