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Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma

Despite advances in deciphering the molecular pathogenesis of diffuse large B-cell lymphoma (DLBCL), patients with relapsed/refractory disease, particularly those with adverse genetic features (e.g., mutated p53 or double hit lymphoma (DHL)) have very poor prognoses, and effective therapies are lack...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Chen, Juan, Tamayo, Archito T., Ruan, Changgeng, Li, Li, Zhou, Shouhao, Shen, Chan, Young, Ken H., Westin, Jason, Davis, Richard E., Hu, Shimin, Medeiros, Leonard J., Ford, Richard J., Pham, Lan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787470/
https://www.ncbi.nlm.nih.gov/pubmed/29416618
http://dx.doi.org/10.18632/oncotarget.20378