PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation

Alpha-synuclein (α-Syn) and phosphatase and tensin homolog deleted on chromosome ten (PTEN)-induced putative kinase (PINK) 1 are proteins found in Lewy bodies, which are a pathological hallmark of Parkinson’s disease (PD). PINK1 overexpression suppresses α-Syn-induced phenotypes and increases lifesp...

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Detalles Bibliográficos
Autores principales: Yang, Weiwei, Wang, Xue, Liu, Jia, Duan, Chunli, Gao, Ge, Lu, Lingling, Yu, Shun, Yang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787472/
https://www.ncbi.nlm.nih.gov/pubmed/29416594
http://dx.doi.org/10.18632/oncotarget.21554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787472/
https://www.ncbi.nlm.nih.gov/pubmed/29416594
http://dx.doi.org/10.18632/oncotarget.21554

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