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MnTBAP therapy attenuates the downregulation of sodium transporters in obstructive kidney disease

Ureteral obstruction is associated with reduced expressions of renal sodium transporters, which contributes to impaired urinary concentrating capacity. In this study, we employed a synthetic mitochondrial superoxide dismutase 2 (SOD2) mimic MnTBAP to investigate the role of mitochondrial oxidative s...

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Detalles Bibliográficos
Autores principales: Liu, Mi, Zhu, Yangyang, Sun, Ying, Wen, Zhaoying, Huang, Songming, Ding, Guixia, Zhang, Aihua, Jia, Zhanjun, Zhang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787475/
https://www.ncbi.nlm.nih.gov/pubmed/29416622
http://dx.doi.org/10.18632/oncotarget.23037