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HDAC inhibitor PAC-320 induces G2/M cell cycle arrest and apoptosis in human prostate cancer

HDAC inhibitors (HDACis) have been demonstrated with profound antiproliferative activities in various tumor types. Previously, we screened several polyoxometalate HDACis based on our p21 luciferase promoter system and demonstrated that such HDACis have antitumor activity. Here, we further investigat...

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Detalles Bibliográficos
Autores principales: Dong, Zhixiong, Yang, Yang, Liu, Shuxia, Lu, Jun, Huang, Baiqu, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787485/
https://www.ncbi.nlm.nih.gov/pubmed/29416632
http://dx.doi.org/10.18632/oncotarget.23070