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Nicotine-enhanced stemness and epithelial-mesenchymal transition of human umbilical cord mesenchymal stem cells promote tumor formation and growth in nude mice

Cigarette smoking is a well-known risk factor in the development and progression of malignant diseases. Nicotine, the major constituent in cigarette smoke, has also shown negative effects on stem cells. Mesenchymal stem cells (MSCs) have been widely demonstrated to migrate into tumors and play key r...

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Detalles Bibliográficos
Autores principales: Li, Tao, Zhang, Jun, Zhang, Jiahui, Zhang, Nannan, Zeng, Yang, Tang, Shengnan, Tao, Zehua, Qu, Xiying, Jia, Jue, Zhu, Wei, Sun, Xiaochun, Chen, Huabiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787492/
https://www.ncbi.nlm.nih.gov/pubmed/29416638
http://dx.doi.org/10.18632/oncotarget.22712