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Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA

Alternative splicing is a critical event in the posttranscriptional regulation of gene expression. To investigate whether this process influences radiation-induced gene expression we defined the effects of ionizing radiation on the generation of alternative transcripts in total cellular mRNA (the tr...

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Detalles Bibliográficos
Autores principales: Wahba, Amy, Ryan, Michael C., Shankavaram, Uma T., Camphausen, Kevin, Tofilon, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787501/
https://www.ncbi.nlm.nih.gov/pubmed/29416646
http://dx.doi.org/10.18632/oncotarget.21672