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Organic cation transporter 3 mediates cisplatin and copper cross-resistance in hepatoma cells

Platinum-based drugs are first-line compounds in the treatment of many solid cancers. Major obstacles are tumors that become resistant and toxic side effects, both largely due to the expression of transporters that mediate the cellular processing of platinum. In this study, we addressed the establis...

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Detalles Bibliográficos
Autores principales: Guttmann, Sarah, Chandhok, Gursimran, Groba, Sara Reinartz, Niemietz, Christoph, Sauer, Vanessa, Gomes, Amanda, Ciarimboli, Giuliano, Karst, Uwe, Zibert, Andree, Schmidt, Hartmut H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787505/
https://www.ncbi.nlm.nih.gov/pubmed/29416650
http://dx.doi.org/10.18632/oncotarget.23142