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Efficient leukocyte depletion by a novel microfluidic platform enables the molecular detection and characterization of circulating tumor cells

RT-qPCR is a highly sensitive approach to detect rare transcripts, as derived from circulating tumor cells (CTCs) in the blood of cancer patients. However, the presence of unwanted leukocytes often leads to false positive results. Here, we evaluated whether the micro-fluidic Parsortix™ technology is...

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Detalles Bibliográficos
Autores principales: Obermayr, Eva, Maritschnegg, Elisabeth, Agreiter, Christiane, Pecha, Nina, Speiser, Paul, Helmy-Bader, Samir, Danzinger, Sabine, Krainer, Michael, Singer, Christian, Zeillinger, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787513/
https://www.ncbi.nlm.nih.gov/pubmed/29416657
http://dx.doi.org/10.18632/oncotarget.22549