Mitochondrial dysfunction activates lysosomal-dependent mitophagy selectively in cancer cells

Molecules designed to target and accumulate in the mitochondria are an emerging therapeutic approach for cancer and other indications. Mitochondria-targeted redox agents (MTAs) induce mitochondrial damage and autophagy in cancer cells. However, the mechanisms for these molecules to induce mitophagy,...

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Detalles Bibliográficos
Autores principales: Biel, Thomas G., Rao, V. Ashutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787530/
https://www.ncbi.nlm.nih.gov/pubmed/29416672
http://dx.doi.org/10.18632/oncotarget.23171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787530/
https://www.ncbi.nlm.nih.gov/pubmed/29416672
http://dx.doi.org/10.18632/oncotarget.23171

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