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Mitochondrial dysfunction activates lysosomal-dependent mitophagy selectively in cancer cells
Molecules designed to target and accumulate in the mitochondria are an emerging therapeutic approach for cancer and other indications. Mitochondria-targeted redox agents (MTAs) induce mitochondrial damage and autophagy in cancer cells. However, the mechanisms for these molecules to induce mitophagy,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787530/ https://www.ncbi.nlm.nih.gov/pubmed/29416672 http://dx.doi.org/10.18632/oncotarget.23171 |