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Dihydroartemisinin selectively inhibits PDGFRα-positive ovarian cancer growth and metastasis through inducing degradation of PDGFRα protein

To develop traditional medicines as modern pharmacotherapies, understanding their molecular mechanisms of action can be very helpful. We have recently reported that Artemisinin and its derivatives, which are clinically used anti-malarial drugs, have significant effects against ovarian cancer, but th...

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Detalles Bibliográficos
Autores principales: Li, Xiaoguang, Ba, Qian, Liu, Yanling, Yue, Qingxi, Chen, Peizhan, Li, Jingquan, Zhang, Haibing, Ying, Hao, Ding, Qiurong, Song, Haiyun, Liu, Hong, Zhang, Ruiwen, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787695/
https://www.ncbi.nlm.nih.gov/pubmed/29387451
http://dx.doi.org/10.1038/celldisc.2017.42