Transcriptome-wide identification of the RNA-binding landscape of the chromatin-associated protein PARP1 reveals functions in RNA biogenesis

Recent studies implicate Poly (ADP-ribose) polymerase 1 (PARP1) in alternative splicing regulation, and PARP1 may be an RNA-binding protein. However, detailed knowledge of RNA targets and the RNA-binding region for PARP1 are unknown. Here we report the first global study of PARP1–RNA interactions us...

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Detalles Bibliográficos
Autores principales: Melikishvili, Manana, Chariker, Julia H, Rouchka, Eric C, Fondufe-Mittendorf, Yvonne N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787697/
https://www.ncbi.nlm.nih.gov/pubmed/29387452
http://dx.doi.org/10.1038/celldisc.2017.43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787697/
https://www.ncbi.nlm.nih.gov/pubmed/29387452
http://dx.doi.org/10.1038/celldisc.2017.43

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