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Assigning function to natural allelic variation via dynamic modeling of gene network induction

More and more natural DNA variants are being linked to physiological traits. Yet, understanding what differences they make on molecular regulations remains challenging. Important properties of gene regulatory networks can be captured by computational models. If model parameters can be “personalized”...

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Detalles Bibliográficos
Autores principales: Richard, Magali, Chuffart, Florent, Duplus‐Bottin, Hélène, Pouyet, Fanny, Spichty, Martin, Fulcrand, Etienne, Entrevan, Marianne, Barthelaix, Audrey, Springer, Michael, Jost, Daniel, Yvert, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787706/
https://www.ncbi.nlm.nih.gov/pubmed/29335276
http://dx.doi.org/10.15252/msb.20177803