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A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei

BACKGROUND: Due to the important role of rifamycin in curing tuberculosis infection, the study on rifamycin has never been stopped. Although RifZ, which locates within the rifamycin biosynthetic cluster, has recently been characterized as a pathway-specific regulator for rifamycin biosynthesis, litt...

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Detalles Bibliográficos
Autores principales: Lei, Chao, Wang, Jingzhi, Liu, Yuanyuan, Liu, Xinqiang, Zhao, Guoping, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787919/
https://www.ncbi.nlm.nih.gov/pubmed/29375035
http://dx.doi.org/10.1186/s12934-018-0863-5