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A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
BACKGROUND: Due to the important role of rifamycin in curing tuberculosis infection, the study on rifamycin has never been stopped. Although RifZ, which locates within the rifamycin biosynthetic cluster, has recently been characterized as a pathway-specific regulator for rifamycin biosynthesis, litt...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787919/ https://www.ncbi.nlm.nih.gov/pubmed/29375035 http://dx.doi.org/10.1186/s12934-018-0863-5 |