Melatonin Mitigates Kainic Acid-Induced Neuronal Tau Hyperphosphorylation and Memory Deficits through Alleviating ER Stress

Kainic acid (KA) exposure causes neuronal degeneration featured by Alzheimer-like tau hyperphosphorylation and memory deficits. Melatonin (Mel) is known to protect hippocampal neurons against KA-induced damage. However, the underlying mechanisms remain elusive. In the current study, we investigated...

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Detalles Bibliográficos
Autores principales: Shi, Cai, Zeng, Jia, Li, Zixi, Chen, Qingjie, Hang, Weijian, Xia, Liangtao, Wu, Yue, Chen, Juan, Shi, Anbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787934/
https://www.ncbi.nlm.nih.gov/pubmed/29416502
http://dx.doi.org/10.3389/fnmol.2018.00005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787934/
https://www.ncbi.nlm.nih.gov/pubmed/29416502
http://dx.doi.org/10.3389/fnmol.2018.00005

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