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The Impact of Amorphisation and Spheronization Techniques on the Improved in Vitro & in Vivo Performance of Glimepiride Tablets

Purpose: Triple solid dispersion adsorbates (TSDads) and spherical agglomerates (SA) present new techniques that extensively enhance dissolution of poorly soluble drugs. The aim of the present study is to hasten the onset of hypoglycemic effect of glimepiride through enhancing its rate of release fr...

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Detalles Bibliográficos
Autores principales: Makar, Rana Refaat, Latif, Randa, Hosni, Ehab Ahmed, El Gazayerly, Omaima Naim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788210/
https://www.ncbi.nlm.nih.gov/pubmed/29399545
http://dx.doi.org/10.15171/apb.2017.067