Novel Doxorubicin Derivatives: Synthesis and Cytotoxicity Study in 2D and 3D in Vitro Models

Purpose: Multidrug resistance (MDR) of tumors to chemotherapeutics often leads to failure of cancer treatment. The aim of the study was to prepare novel MDR-overcoming chemotherapeutics based on doxorubicin (DOX) derivatives and to evaluate their efficacy in 2D and 3D in vitro models. Methods: To ov...

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Detalles Bibliográficos
Autores principales: Akasov, Roman, Drozdova, Maria, Zaytseva-Zotova, Daria, Leko, Maria, Chelushkin, Pavel, Marc, Annie, Chevalot, Isabelle, Burov, Sergey, Klyachko, Natalia, Vandamme, Thierry, Markvicheva, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788214/
https://www.ncbi.nlm.nih.gov/pubmed/29399549
http://dx.doi.org/10.15171/apb.2017.071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788214/
https://www.ncbi.nlm.nih.gov/pubmed/29399549
http://dx.doi.org/10.15171/apb.2017.071

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