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Strategies for Improving siRNA-Induced Gene Silencing Efficiency

Purpose: Human telomerase reverse transcriptase (hTERT) plays a crucial role in tumorigenesis and progression of cancers. Gene silencing of hTERT by short interfering RNA (siRNA) is considered as a promising strategy for cancer gene therapy. Various algorithms have been devised for designing a high...

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Detalles Bibliográficos
Autores principales: Safari, Fatemeh, Rahmani Barouji, Solmaz, Tamaddon, Ali Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788215/
https://www.ncbi.nlm.nih.gov/pubmed/29399550
http://dx.doi.org/10.15171/apb.2017.072